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 Formulary Chapter 2: Cardiovascular system - Full Chapter
Notes:

Cardiovascular Documents

 Details...
02.12  Expand sub section  Lipid-regulating drugs
02.12  Expand sub section  Bile acid sequestrants
Colestyramine
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First Choice
Green 1
 
Colesevelam (Cholestagel)
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Restricted Drug Restricted
Amber

(unlicensed indication) Approved for gastroenterology use only.

For hyperbilirubinaemia, as a second line option where colestyramine is not tolerated

 

 
   
02.12  Expand sub section  Ezetimibe
Ezetimibe (Ezetrol)
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Formulary
Green 2

Second line option when statins not tolerated. Prescribe generically.

 

 
Link  NICE TA385: Ezetimibe for treating primary heterozygous-familial and non-familial hypercholesterolaemia
   
02.12  Expand sub section  Fibrates
Bezafibrate
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Formulary
Green
 
   
02.12  Expand sub section  Statins to top
Atorvastatin
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First Choice
Green 1
 
Pravastatin
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Second Choice
Green 2

2nd line agent. Atorvastatin 1st line.

 
   
Simvastatin
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Second Choice
Green 2

2nd line after atorvastatin.

Current evidence suggests that patient should be treated with not less than 40mg daily for secondary prevention of ischemic events [unless prescribed an interacting drug]

 

 
   
02.12  Expand sub section  Nicotinic acid group
02.12  Expand sub section  Omega-3 fatty acid compounds
Omega-3-Acid Ethyl Esters  (Prestylon)
(Hypertriglyceridaemia)
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Restricted Drug Restricted
Amber

Consultant lipidologist initiation for refractory hypertriglyceridaemia. 

 
   
 ....
 Non Formulary Items
Acipimox  (Olbetam®)

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Non Formulary
 
Alirocumab  (Praluent)

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Non Formulary
Link  NICE TA393: Alirocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia
 
Atorvastatin and Ezetimibe  (Atozet)

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Non Formulary
 
Bezafibrate  (Bezalip®)

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Non Formulary
 
Bezafibrate  (Bezalip® Mono)

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Non Formulary
 
Ciprofibrate  (Modalim®)

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Non Formulary
 
Colestipol  (Colestid)

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Non Formulary
 
Evolocumab  (Repatha )

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Non Formulary
Link  NICE TA394: Evolocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia
 
Fenofibrate

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Non Formulary
 
Fenofibrate  (Lipantil®)

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Non Formulary
 
Fenofibrate  (Supralip® 160)

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Non Formulary
 
Fluvastatin  (Lescol®)

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Non Formulary
 
Fluvastatin  (Lescol® XL)

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Non Formulary
 
Gemifibrozil

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Non Formulary
 
Gemifibrozil  (Lopid®)

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Non Formulary
 
Lomitapide  (Lojuxta▼)

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Non Formulary
High Cost Medicine
 
Nicotinic Acid  (Niaspan)

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Non Formulary
 
Nicotinic acid/ laropiprant  (Tredaptive )

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Non Formulary
 
Omega-3-Acid Ethyl Esters  (Omacor)

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Non Formulary

See Herefordshire LPT except following consultant lipidologist initiation for refractory hypertriglyceridaemia. Low Value Medicine

 
Omega-3-Marine Triglycerides  (Maxepa)

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Non Formulary

See Herefordshire LPT except following consultant lipidologist initiation for refractory hypertriglyceridaemia. Low Value Medicine

 

 
Rosuvastatin

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Non Formulary

Lack of clinical and cost effectiveness

 

 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Green

Suitable for use in primary care  

Amber

Specialist initiation. Shared care in place  

Red

Red do not use..  

Advice

Some formulations restricted  

Black

NICE "Do not do"  

Green 1

1st line option  

Green 2

2nd line option  

Green 3

3rd line option only  

Not Recomended / Black

Low Value Medicine not recommended for use - see NHSE guidelines  

OTC

This preparation should be bought over the counter for self-care  

Red Amber

Check product description for traffic light status  

Red Black

Low Value Medicine  

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